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Urine-derived induced pluripotent/neural stem cells for modeling neurological diseases

13 May 2021

Abstract excerpt

Neurological diseases are mainly modeled using rodents through gene editing, surgery or injury approaches. However, differences between humans and rodents in terms of genetics, neural development, and physiology pose limitations on studying disease pathogenesis in rodent models for neuroscience research. In the past decade, the generation of induced pluripotent stem cells (iPSCs) and induced neural stem cells...

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PMID: 33985584
DOI: 10.1186/s13578-021-00594-5

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