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Applying and testing the conveniently optimized enzyme mismatch cleavage method to clinical DNA diagnosis.

Molecular genetics and metabolism - 1 Nov 2012

Niida Yo, Kuroda Mondo, Mitani Yusuke, Okumura Akiko, Yokoi Ayano

Abstract excerpt

Establishing a simple and effective mutation screening method is one of the most compelling problems with applying genetic diagnosis to clinical use. Because there is no reliable and inexpensive screening system, amplifying by PCR and performing direct sequencing of every coding exon is the gold...

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Identifiers

PMID: 23022073
DOI: 10.1016/j.ymgme.2012.09.008

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CEL
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23022073-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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