Article
DNA-based diagnostics in the study of heritable and acquired disorders.
The Journal of laboratory and clinical medicine - 1 Apr 1995
Shikata H, Utsumi N, Kuivaniemi H, Tromp G
Abstract excerpt
Recent advances in molecular biology techniques have made DNA diagnostics a reality. A major advance was the development of the polymerase chain reaction, which allows the direct analysis of a region of a known gene from minute quantities of template DNA. The DNA can even be isolated from such so...
Topics
- Animals
- Base Sequence
- DNA
- Genetic Diseases, Inborn
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
