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Article

CD4+CD25+CD127- assessment as a surrogate phenotype for FOXP3+ regulatory T cells in HIV-1 infected viremic and aviremic subjects.

Cytometry. Part B, Clinical cytometry - 1 Jan 2000

Saison Julien, Demaret Julie, Venet Fabienne, Chidiac Christian, Malcus Christophe, Poitevin-Later Francoise, Tardy Jean-Claude, Ferry Tristan, Monneret Guillaume

Abstract excerpt

BACKGROUND: Although likely pivotal, the role of regulatory T cells (Tregs) in HIV pathogenesis remains elusive. This can be partly explained by analytical issues regarding their phenotypic identification in clinical studies. Instead of intracellular FOXP3 staining, CD4+CD25+CD127- phenotype has been proposed as an alternative to identify Tregs in clinical samples. However, its use remains controversial in...

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Identifiers

PMID: 23019018
DOI: 10.1002/cyto.b.21047

Genes

FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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