Article
Plasmodium vivax: induction of CD4+CD25+FoxP3+ regulatory T cells during infection are directly associated with level of circulating parasites.
PloS one - 10 Mar 2010
Bueno Lilian Lacerda, Morais Cristiane Guimarães, Araújo Fernanda Fortes, Gomes Juliana Assis Silva, Corrêa-Oliveira Rodrigo, Soares Irene Silva, Lacerda Marcus Vinícius, Fujiwara Ricardo Toshio, Braga Erika Martins
Abstract excerpt
Circulation CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) have been associated with the delicate balancing between control of overwhelming acute malaria infection and prevention of immune pathology due to disproportionate inflammatory responses to erythrocytic stage of the parasite. While the role of Tregs has been well-documented in murine models and P. falciparum infection, the phenotype and function of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.