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Article

Altered phenotype of regulatory T cells associated with lack of human immunodeficiency virus (HIV)-1-specific suppressive function.

Clinical and experimental immunology - 1 Nov 2011

Burton C T, Westrop S J, Eccles-James I, Boasso A, Nelson M R, Bower M, Imami N

Abstract excerpt

Mechanisms by which CD4+ regulatory T cells (T(regs)) mediate suppression of virus-specific responses remain poorly defined. Adenosine, mediated via CD39 and CD73, has been shown to play a role in the action of murine T(regs) . In this study we investigate the phenotype of T(regs) in the context of human immunodeficiency virus (HIV)-1 infection, and the function of these cells in response to HIV-1-Gag and...

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Source

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Identifiers

PMID: 21985365
DOI: 10.1111/j.1365-2249.2011.04451.x
PMCID: PMC3219894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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