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Article

p53 and ΔNp63α Coregulate the Transcriptional and Cellular Response to TGFβ and BMP Signals

20 Feb 2015

Abstract excerpt

UNLABELLED: The TGFβ superfamily regulates a broad range of cellular processes, including proliferation, cell-fate specification, differentiation, and migration. Molecular mechanisms underlying this high degree of pleiotropy and cell-type specificity are not well understood. The TGFβ family is composed of two branches: (i) TGFβs, activins, and nodals, which signal through SMAD2/3, and (ii) bone morphogenetic...

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PMID: 25700283
DOI: 10.1158/1541-7786.mcr-14-0152-t

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