Article
Tyrosine kinase receptor status in endometrial stromal sarcoma: an immunohistochemical and genetic-molecular analysis.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Nov 2012
Cossu-Rocca Paolo, Contini Marcella, Uras Maria Gabriela, Muroni Maria Rosaria, Pili Francesca, Carru Ciriaco, Bosincu Luisanna, Massarelli Giovannino, Nogales Francisco F, De Miglio Maria Rosaria
Abstract excerpt
Endometrial stromal sarcomas (ESS) are rare uterine malignant mesenchymal neoplasms, which are currently treated by surgery, as effective adjuvant therapies have not yet been established. Tyrosine kinase inhibitors have rarely been applied in ESS therapy, with few reports describing imatinib responsivity. The aim of this study was to analyze the status of different tyrosine kinase receptors in an ESS series, in...
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