Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uterine sarcomas express KIT protein but lack mutation(s) in exon 11 or 17 of c-KIT.

Gynecologic oncology - 1 Oct 2003

Rushing R Scott, Shajahan Shahin, Chendil Damodaran, Wilder James L, Pulliam Joseph, Lee Eun Y, Ueland Frederick R, van Nagell John R, Ahmed Mansoor M, Lele Subodh M

Abstract excerpt

OBJECTIVE: Several tumors express the protein product of the protooncogene c-KIT. Some of these respond to imatinib mesylate, a tyrosine kinase inhibitor. The tumors that respond frequently have mutation(s) in exon 11 of c-KIT that encodes for the regulatory juxtamembrane helix. Some tumors that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Neoplasm
Share to Exons
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leiomyosarcoma

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins c-kit

Share to Sarcoma

Share to Uterine Neoplasms

Source

Identifiers

PMID: 14529657
DOI: 10.1016/s0090-8258(03)00442-6

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14529657-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uterine sarcomas express KIT protein but lack mutation(s) in exon 11 or 17 of c-KIT.PMID 14529657Read ↗

c-Kit Expression in Patients with Uterine LeiomyosarcomasSemantic proximity Read ↗

Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement.Semantic proximity Read ↗

Immunohistochemical evaluation of KIT expression in sarcomas of the gynecologic region.Semantic proximity Read ↗

MED12 alterations in both human benign and malignant uterine soft tissue tumors.Semantic proximity Read ↗

Tyrosine kinase receptor status in endometrial stromal sarcoma: an immunohistochemical and genetic-molecular analysis.Semantic proximity Read ↗

Expression of platelet-derived growth factor receptor in low-grade endometrial stromal sarcomas in the absence of activating mutations.Semantic proximity Read ↗

Protein expression of KIT and gene mutation of c-kit and PDGFRs in Ewing sarcomas.Semantic proximity Read ↗

PTEN mutations in uterine sarcomas.Semantic proximity Read ↗

Low frequency of somatic mutations in uterine sarcomas: a molecular analysis and review of the literature.Semantic proximity Read ↗

Molecular Analysis of the JAZF1-JJAZ1 Gene Fusion by RT-PCR and Fluorescence In Situ Hybridization in Endometrial Stromal NeoplasmsSemantic proximity Read ↗

Detection of c-kit-activating mutations in gastrointestinal stromal tumors by high-resolution amplicon melting analysis.Semantic proximity Read ↗

C-kit Mutations in Endometrial Cancer: Correlation with Tumor Histologic Type.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.