Article
EGFR isoforms and gene regulation in human endometrial cancer cells.
Molecular cancer - 25 Jun 2010
Albitar Lina, Pickett Gavin, Morgan Marilee, Wilken Jason A, Maihle Nita J, Leslie Kimberly K
Abstract excerpt
BACKGROUND: Epidermal growth factor (EGF) and its receptor (EGFR) constitute a principal growth-promoting pathway in endometrial cancer cells. Pre-clinical studies were undertaken to compare the expression of EGFR isoforms and the downstream effects of activating or blocking EGFR function in Ishikawa H cells, derived from a moderately differentiated type I endometrioid adenocarcinoma, or in Hec50co cells, derived...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
