Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-1 receptor antagonist gene polymorphism increases susceptibility to septic shock in children with acute lymphoblastic leukemia.

The Pediatric infectious disease journal - 1 Feb 2013

Zapata-Tarrés Marta, Arredondo-García Jose Luis, Rivera-Luna Roberto, Klünder-Klünder Miguel, Mancilla-Ramírez Javier, Sánchez-Urbina Rocío, Vázquez-Cruz Margarita Yolanda, Juárez-Villegas Luis Enrique, Palomo-Colli Miguel Angel

Abstract excerpt

BACKGROUND: Interleukin-1 receptor antagonist polymorphism (ILRN) 2 (ILRN*2) has been associated with a poor outcome in septic patients because of an elevated production of anti-inflammatory cytokines. In >70% of patients, morbidity and mortality in childhood acute lymphoblastic leukemia is caused by infections. The aim of this study was to determine the association between this polymorphism and the frequency of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Fever

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin 1 Receptor Antagonist Protein

Share to Logistic Models

Share to Neutropenia

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Shock, Septic

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 23014359
DOI: 10.1097/INF.0b013e31827566dd

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-1 receptor antagonist gene polymorphism increases susceptibility to septic shock in children with acute lymphoblastic leukemia.PMID 23014359Read ↗

Polymorphism within the second intron of the IL-1 receptor antagonist gene in patients with hematopoietic malignancies.Semantic proximity Read ↗

Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis.Semantic proximity Read ↗

Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients.Semantic proximity Read ↗

Clinical Implication of Toll-Like Receptors (TLR2 and TLR4) Polymorphisms in Adult Patients with Acute B-cell Lymphoblastic Leukemia.Semantic proximity Read ↗

Infections during induction therapy of childhood acute lymphoblastic leukemia--no association to mannose-binding lectin deficiency.Semantic proximity Read ↗

A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.Semantic proximity Read ↗

Distribution of interleukin-1 receptor antagonist genotypes in sudden unexpected death in infancy (SUDI); unexplained SUDI have a higher frequency of allele 2.Semantic proximity Read ↗

Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock.Semantic proximity Read ↗

Febrile seizures: interleukin 1beta and interleukin-1 receptor antagonist polymorphisms.Semantic proximity Read ↗

[Genomic polymorphism within interleukin-1 family cytokines influences the outcome of septic patients].Semantic proximity Read ↗

Genetics and genomics in pediatric septic shock.Semantic proximity Read ↗

Influence of interleukin-1 receptor antagonist gene polymorphism on disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.