Article
Genome-wide linkage scan for psoriasis susceptibility loci in multiplex Tunisian families.
The British journal of dermatology - 1 Mar 2013
Ammar M, Bouchlaka-Souissi C, Helms C A, Zaraa I, Jordan C T, Anbunathan H, Bouhaha R, Kouidhi S, Doss N, Dhaoui R, Ben Osman A, Ben Ammar El Gaied A, Marrakchi R, Mokni M, Bowcock A M
Abstract excerpt
BACKGROUND: Psoriasis is a relapsing chronic inflammatory skin disease affecting all population groups, with a peak prevalence of 3% in northern European and Scandinavian caucasians. Epidemiological studies have implicated a genetic component to psoriasis. In the past 12 years multiple genome-wide linkage analyses have identified putative susceptibility loci on several chromosomes, with a major locus in the major...
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