Article
Confirmation of psoriasis susceptibility loci on chromosome 6p21 and 20p13 in French families.
The Journal of investigative dermatology - 1 Jun 2007
Lesueur Fabienne, Lefèvre Caroline, Has Cristina, Guilloud-Bataille Michel, Oudot Tiphaine, Mahé Emmanuel, Lahfa Morad, Mansouri Samira, Mosharraf-Olmolk Haydeh, Sobel Eric, Heath Simon, Lathrop Mark, Dizier Marie-Hélène, Prud'Homme Jean-François, Fischer Judith
Abstract excerpt
Plaque psoriasis is a chronic inflammatory disorder of the skin. It is inherited as a multifactorial trait, with a strong genetic component. Linkage studies have identified a large number of disease loci, but very few could be replicated in independent family sets. In this study, we present the results of a genome-wide scan carried out in 14 French extended families. Candidate regions were then tested in a second...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
