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Article

Complex oncogene dependence in microRNA-125a–induced myeloproliferative neoplasms

24 Sept 2012

Abstract excerpt

Deregulation of microRNA (miRNA) expression can lead to cancer initiation and progression. However, limited information exists on the function of miRNAs in cancer maintenance. We examined these issues in the case of myeloproliferative diseases and neoplasms (MPN), a collection of hematopoietic neoplasms regarded as preleukemic, thereby representing early neoplastic states. We report here that microRNA-125a...

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PMID: 23012470
DOI: 10.1073/pnas.1213196109

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