Article
Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.
Translational psychiatry - 25 Sept 2012
Meier S, Mattheisen M, Vassos E, Strohmaier J, Treutlein J, Josef F, Breuer R, Degenhardt F, Mühleisen T W, Müller-Myhsok B, Steffens M, Schmael C, McMahon F J, Nöthen M M, Cichon S, Schulze T G, Rietschel M, Kelsoe John R, Greenwood Tiffany A, Nievergelt Caroline M, Barrett Thomas B, McKinney Rebecca, Shilling Paul D, Schork Nicholas J, Smith Erin N, Bloss Cinnamon S, Nurnberger John, Edenberg Howard J, Foroud Tatiana, Koller Daniel L, Gershon Elliot S, Liu Chun-Yu, Badner Judith A, Scheftner William, Lawson William B, Nwulia Evaristus A, Hipolito Maria, Coryell William, Rice John, Byerley William, McMahon Francis, Chen David T W, Schulze Thomas G, Berrettini Wade, Potash James B, Zandi Peter P, Mahon Pamela B, McInnis Melvin, Craig David, Szelinger Szabolcs
Abstract excerpt
Research suggests that clinical symptom dimensions may be more useful in delineating the genetics of bipolar disorder (BD) than standard diagnostic models. To date, no study has applied this concept to data from genome-wide association studies (GWAS). We performed a GWAS of factor dimensions in 9...
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