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Article

Loss of Desmocollin 3 in skin tumor development and progression.

Molecular carcinogenesis - 1 Jul 2012

Chen Jiangli, O'Shea Charlene, Fitzpatrick James E, Koster Maranke I, Koch Peter J

Abstract excerpt

Desmocollin 3 (DSC3) is a desmosomal cadherin that is required for maintaining cell adhesion in the epidermis as demonstrated by the intra-epidermal blistering observed in Dsc3 null skin. Recently, it has been suggested that deregulated expression of DSC3 occurs in certain human tumor types. It is not clear whether DSC3 plays a role in the development or progression of cancers arising in stratified epithelia such...

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Source

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Identifiers

PMID: 21681825
DOI: 10.1002/mc.20818
PMCID: PMC3178010

Genes

DSC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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