Article
Extracellularly truncated desmoglein 1 compromises desmosomes in MDCK cells.
Molecular membrane biology - 1 Jan 2000
Serpente N, Marcozzi C, Roberts G A, Bao Q, Angst B D, Hirst E M, Burdett I D, Buxton R S, Magee A I
Abstract excerpt
The formation and stability of epithelial tissue involves cell adhesion and the connection of the intermediate filaments of contiguous cells, mediated by desmosomes. The cadherin family members Desmocollins (Dsc) and Desmogleins (Dsg) mediate desmosome extracellular adhesion. The main intracellular molecules identified linking Dscs and Dsgs with the intermediate filament network are Plakoglobin (PG), Plakophilins...
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