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Article

Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23.

BMC medical genetics - 24 Sept 2012

Zhao Jianhua, Deliard Sandra, Aziz Ali Rahim, Grant Struan F A

Abstract excerpt

BACKGROUND: There is evidence that one of the key type 2 diabetes (T2D) loci identified by GWAS exerts its influence early on in life through its impact on pediatric BMI. This locus on 10q23 harbors three genes, encoding hematopoietically expressed homeobox (HHEX), insulin-degrading enzyme (IDE) and kinesin family member 11 (KIF11), respectively. METHODS: We analyzed the impact of adipogeneis on the mRNA and...

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Identifiers

PMID: 22998375
DOI: 10.1186/1471-2350-13-89
PMCID: PMC3514277

Genes

HHEX
IDE
KIF11

Provenance

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