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Article

Genetic load is associated with hypothalamic-pituitary-adrenal axis dysregulation in macaques.

Genes, brain, and behavior - 1 Nov 2012

Ferguson B, Hunter J E, Luty J, Street S L, Woodall A, Grant K A

Abstract excerpt

Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis pathway is associated with several neuropsychiatric disorders, including post-traumatic stress disorder (PTSD), major depressive disorder (MDD), schizophrenia and alcohol abuse. Studies have demonstrated an association between HPA axis dysfunction and gene variants within the cortisol, serotonin and opioid signaling pathways. We characterized...

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Identifiers

PMID: 22998353
DOI: 10.1111/j.1601-183X.2012.00856.x
PMCID: PMC3595329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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