Article
Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction.
Neuroscience letters - 25 Apr 2008
Proudnikov Dmitri, Hamon Sara, Ott Jurg, Kreek Mary Jeanne
Abstract excerpt
The melanocortin receptor type 2 (MC2R or adrenocorticotropic hormone, ACTH receptor) gene (MC2R) encodes a protein involved in regulation of adrenal cortisol secretion, important in the physiological response to stressors. A variant of MC2R, -179A>G, results in reduction of promoter activity and...
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