Article
TPH2 5'- and 3'-regulatory polymorphisms are differentially associated with HPA axis function and self-injurious behavior in rhesus monkeys.
Genes, brain, and behavior - 1 Apr 2010
Chen G-L, Novak M A, Meyer J S, Kelly B J, Vallender E J, Miller G M
Abstract excerpt
Tryptophan hydroxylase-2 (TPH2) synthesizes neuronal serotonin and is linked to numerous behavioral traits. We have previously characterized the functionality of polymorphisms (especially 2051A>C) in 3'-untranslated region (3'-UTR) of rhesus monkey TPH2 (rhTPH2). This study further assessed the f...
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