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Article

Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration.

Cardiovascular research - 1 Jan 2013

Boukens Bas J, Hoogendijk Mark G, Verkerk Arie O, Linnenbank Andre, van Dam Peter, Remme Carol-Ann, Fiolet Jan W, Opthof Tobias, Christoffels Vincent M, Coronel Ruben

Abstract excerpt

AIMS: Transgenic mice are frequently used to investigate the role of genes involved in cardiac conduction. The QRS duration calculated from the electrocardiogram (ECG) is a commonly used measure for ventricular conduction time. However, the relation between ventricular activation and QRS duration calculated from a mouse surface ECG is not well understood. We aim to relate ventricular activation and repolarization...

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Identifiers

PMID: 22997159
DOI: 10.1093/cvr/cvs299

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