Article
Extracting actionable information from genome scans.
Genetic epidemiology - 1 Jan 2013
Bacanu Silviu-Alin, Kendler Kenneth S
Abstract excerpt
Genome-wide association studies discovered numerous genetic variants significantly associated with various phenotypes. However, significant signals explain only a small portion of the variation in many traits. One explanation is that missing variation is found in "suggestive signals," i.e., variants with reasonably small P-values. However, it is not clear how to capture this information and use it optimally to...
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