Article

Identification of Influential Variants in Significant Aggregate Rare Variant Tests

2020-10-03

Abstract excerpt

<h4>Introduction</h4> Studies that examine the role of rare variants in both simple and complex disease are increasingly common. Though the usual approach of testing rare variants in aggregate sets is more powerful than testing individual variants, it is of interest to identify the variants that are plausible drivers of the association. We present a novel method for prioritization of rare variants after a signifi...

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Literature Corpus work: da3b24c6-8322-503f-bfc4-70fe5e8f7e95
DOI: 10.1101/2020.10.01.322644

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