Article

Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole Genome Sequencing Studies

2019-02-17

Abstract excerpt

Whole genome sequencing (WGS) studies are being widely conducted to identify rare variants associated with human diseases and disease-related traits. Classical single-marker association analyses for rare variants have limited power, and variant-set based analyses are commonly used to analyze rare variants. However, existing variant-set based approaches need to pre-specify genetic regions for analysis, and hence ar...

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Literature Corpus work: ad0c79c9-2bfb-50e4-b458-6c24fcc93916
DOI: 10.1101/552950

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