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Article

Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins.

The Journal of biological chemistry - 2 Nov 2012

Qin Sheng-Ying, Hu Dan, Matsumoto Kana, Takeda Koh, Matsumoto Naoki, Yamaguchi Yoshiki, Yamamoto Kazuo

Abstract excerpt

Malectin is an endoplasmic reticulum-resident lectin, which recognizes di-glucosylated Glc(2)Man(9)GlcNAc(2) (G2M9) N-glycans on newly synthesized glycoproteins. We previously demonstrated that malectin preferentially associates with misfolded glycoproteins and inhibits their secretion (Chen, Y., Hu, D., Yabe, R., Tateno, H., Qin, S. Y., Matsumoto, N., Hirabayashi, J., and Yamamoto, K. (2011) Mol. Biol. Cell 22,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22988243
DOI: 10.1074/jbc.M112.394288
PMCID: PMC3488078

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