Article
mu-Opioid receptor cell surface expression is regulated by its direct interaction with Ribophorin I.
Molecular pharmacology - 1 Jun 2009
Ge Xin, Loh Horace H, Law Ping-Yee
Abstract excerpt
The trafficking of the mu-opioid receptor (MOR), a member of the rhodopsin G protein-coupled receptor (GPCR) family, can be regulated by interaction with multiple cellular proteins. To determine the proteins involved in receptor trafficking, using the targeted proteomic approach and mass spectrometry analysis, we have identified that Ribophorin I (RPNI), a component of the oligosaccharide transferase complex,...
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