Article
How a common variant in the growth factor receptor gene, NTRK1, affects white matter.
Bioarchitecture - 1 Jan 2000
Braskie Meredith N, Jahanshad Neda, Toga Arthur W, McMahon Katie L, de Zubicaray Greig I, Martin Nicholas G, Wright Margaret J, Thompson Paul M
Abstract excerpt
Growth factors and their receptors are important for cellular migration as well as axonal guidance and myelination in the brain. They also play a key role in programmed cell death, and are implicated in a number of mental illnesses. Recently, we reported that healthy young adults who carry the T allele variant in the growth factor gene, NTRK1 (at location rs6336), had lower white matter integrity than...
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