Article
CNTNAP2 polymorphisms and structural brain connectivity: a diffusion-tensor imaging study.
Journal of psychiatric research - 1 Oct 2013
Clemm von Hohenberg Christian, Wigand Marlene C, Kubicki Marek, Leicht Gregor, Giegling Ina, Karch Susanne, Hartmann Annette M, Konte Bettina, Friedl Marion, Ballinger Thomas, Eckbo Ryan, Bouix Sylvain, Jäger Lorenz, Shenton Martha E, Rujescu Dan, Mulert Christoph
Abstract excerpt
CNTNAP2 is a gene on chromosome 7 that has shown associations with autism and schizophrenia, and there is evidence that it plays an important role for neuronal synchronization and brain connectivity. In this study, we assessed the relationship between Diffusion Tensor Imaging (DTI), a putative marker of anatomical brain connectivity, and multiple single nucleotide polymorphisms (SNPs) spread out over this large...
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