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Article

A p53-Pax2 pathway in kidney development: implications for nephrogenesis.

PloS one - 1 Jan 2012

Saifudeen Zubaida, Liu Jiao, Dipp Susana, Yao Xiao, Li Yuwen, McLaughlin Nathaniel, Aboudehen Karam, El-Dahr Samir S

Abstract excerpt

Congenital reduction in nephron number (renal hypoplasia) is a predisposing factor for chronic kidney disease and hypertension. Despite identification of specific genes and pathways in nephrogenesis, determinants of final nephron endowment are poorly understood. Here, we report that mice with ger...

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Share to Epistasis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 22984579
DOI: 10.1371/journal.pone.0044869
PMCID: PMC3440354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22984579-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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