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Article

Development of the renal glomerulus: good neighbors and good fences

10 Jan 2008

Abstract excerpt

The glomerulus of the mammalian kidney is an intricate structure that contains an unusual filtration barrier that retains higher molecular weight proteins and blood cells in the circulation. Recent studies have changed our conception of the glomerulus from a relatively static structure to a dynamic one, whose integrity depends on signaling between the three major cell lineages: podocytes, endothelial and...

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PMID: 18184729
DOI: 10.1242/dev.001081

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