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Article

Disorders of left-right asymmetry: heterotaxy and situs inversus.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 Nov 2009

Sutherland Mardi J, Ware Stephanie M

Abstract excerpt

Cilia function is critical to the development of proper organ laterality. Primary ciliary dyskinesia (PCD) causes randomization of situs. Heterotaxy, or situs ambiguus, is an abnormal arrangement of the thoracic and abdominal organs that results in congenital anomalies. Animal models and developmental biological approaches have defined pathways required during embryogenesis for proper left-right pattern...

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Identifiers

PMID: 19876930
DOI: 10.1002/ajmg.c.30228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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