Article
Negative NKX2-1 (TTF-1) as temporary surrogate marker for treatment selection during EGFR-mutation analysis in patients with non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2012
Vincenten Julien, Smit Egbert F, Vos Wim, Grünberg Katrien, Postmus Pieter E, Heideman Daniëlle A M, Snijders Peter J F, Meijer Gerrit, Kuik Joop, Witte Birgit I, Thunnissen Erik
Abstract excerpt
INTRODUCTION: In the past decade, major progress has been made toward personalized medical treatment of non-small-cell lung cancer (NSCLC) through the discovery of epithelial growth factor receptor (EGFR) mutations. However, mutation analysis takes extra time and additional costs in the diagnosti...
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