CDX2 as a useful marker of colorectal adenocarcinoma metastases to lung in pre-operative biopsy specimens.

Abstract excerpt

Although distinguishing metastatic colorectal adenocarcinoma from primary lung adenocarcinoma is often difficult, pre- or intra-operative identification is very important, as the resection areas for each diagnosis differ substantially. CDX2, a recently cloned homeobox gene, represents a highly specific and sensitive marker of colorectal adenocarcinoma. We evaluated CDX2 expression using pre- and intra-operative...

Topics

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• Adenocarcinoma
• Biopsy
• CDX2 Transcription Factor
• Homeodomain Proteins
• Immunoenzyme Techniques