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Article

Coevolution reveals a network of human proteins originating with multicellularity.

Molecular biology and evolution - 1 Feb 2013

Bezginov Alexandr, Clark Gregory W, Charlebois Robert L, Dar Vaqaar-un-Nisa, Tillier Elisabeth R M

Abstract excerpt

Protein interaction networks play central roles in biological systems, from simple metabolic pathways through complex programs permitting the development of organisms. Multicellularity could only have arisen from a careful orchestration of cellular and molecular roles and responsibilities, all pr...

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PMID: 22977115
DOI: 10.1093/molbev/mss218
PMCID: PMC3548307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22977115-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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