piRNAs warrant investigation in Rett Syndrome: an omics perspective.

Abstract excerpt

Mutations in the MECP2 gene are found in a large proportion of girls with Rett Syndrome. Despite extensive research, the principal role of MeCP2 protein remains elusive. Is MeCP2 a regulator of genes, acting in concert with co-activators and co-repressors, predominantly as an activator of target genes or is it a methyl CpG binding protein acting globally to change the chromatin state and to supress transcription...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cerebellum
• Share to Long Interspersed Nucleotide Elements
• Share to Methyl-CpG-Binding Protein 2