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Article

Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets.

BMC medical genetics - 20 Jun 2007

Jordan ChaRandle, Li Hong Hua, Kwan Helen C, Francke Uta

Abstract excerpt

BACKGROUND: MeCP2, methyl-CpG-binding protein 2, binds to methylated cytosines at CpG dinucleotides, as well as to unmethylated DNA, and affects chromatin condensation. MECP2 mutations in females lead to Rett syndrome, a neurological disorder characterized by developmental stagnation and regression, loss of purposeful hand movements and speech, stereotypic hand movements, deceleration of brain growth, autonomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1 Receptor-Associated Kinases

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Source

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Identifiers

PMID: 17584923
DOI: 10.1186/1471-2350-8-36
PMCID: PMC1931432

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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