Article
Single nucleotide polymorphisms in thymic stromal lymphopoietin gene are not associated with allergic rhinitis susceptibility in Chinese subjects.
BMC medical genetics - 13 Sept 2012
Zhang Yuan, Song Xiaohong, Zhao Yanming, Zhang Luo, Bachert Claus
Abstract excerpt
BACKGROUND: Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine, implicated in the development and progression of allergic diseases. Recent studies have demonstrated significantly increased expression and synthesis of TSLPin nasal mucosa of patients with allergic rhinitis (AR), compared with nonallergic control subjects. Also, there is significant correlation between the level of TSLP mRNA...
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