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Article

Association between lamotrigine concentrations and ABCB1 polymorphisms in patients with epilepsy.

Therapeutic drug monitoring - 1 Oct 2012

Lovrić Mila, Božina Nada, Hajnšek Sanja, Kuzman Martina Rojnić, Sporiš Davor, Lalić Zdenka, Božina Tamara, Granić Paula

Abstract excerpt

BACKGROUND: Epilepsy is treated with a variety of anticonvulsants that are often used concomitantly. Therefore, therapeutic drug monitoring is often necessary. Along with clinical and environmental factors, genetic predisposition has been recognized to be relevant for interindividual variability in drug response. Polymorphic transporter proteins such as P-glycoprotein significantly influence pharmacokinetics and...

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Source

Identifiers

PMID: 22972536
DOI: 10.1097/FTD.0b013e31826517c6

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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