Pharmacogenetics of the antiepileptic drugs phenytoin and lamotrigine.

doi:10.1515/DMDI.2011.008

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Article

Pharmacogenetics of the antiepileptic drugs phenytoin and lamotrigine.

Drug metabolism and drug interactions - 1 Jan 2011

López Marisol, Dorado Pedro, Monroy Nancy, Alonso María Elisa, Jung-Cook Helgi, Machín Esther, Peñas-Lledó Eva, Llerena Adrián

Abstract excerpt

Patients treated with antiepileptic drugs can exhibit large interindividual variability in clinical efficacy or adverse effects. This could be partially due to genetic variants in genes coding for proteins that function as drug metabolizing enzymes, drug transporters or drug targets. The purpose of this article is to provide an overview of the current knowledge on the pharmacogenetics of two commonly prescribed...

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Identifiers

PMID: 21557672
DOI: 10.1515/DMDI.2011.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.