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Article

Human-specific CpG "beacons" identify loci associated with human-specific traits and disease.

Epigenetics - 1 Oct 2012

Bell Christopher G, Wilson Gareth A, Butcher Lee M, Roos Christian, Walter Lutz, Beck Stephan

Abstract excerpt

Regulatory change has long been hypothesized to drive the delineation of the human phenotype from other closely related primates. Here we provide evidence that CpG dinucleotides play a special role in this process. CpGs enable epigenome variability via DNA methylation, and this epigenetic mark fu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22968434
DOI: 10.4161/epi.22127
PMCID: PMC3469460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22968434-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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