Article
G894T polymorphism of eNOS gene is a predictor of response to combination of inhaled corticosteroids with long-lasting β2-agonists in asthmatic children.
Pharmacogenomics - 1 Sept 2012
Iordanidou Maria, Paraskakis Emmanouil, Tavridou Anna, Paschou Peristera, Chatzimichael Athanasios, Manolopoulos Vangelis G
Abstract excerpt
AIM: Nitric oxide synthase enzymes have an important role in airway inflammation in asthmatic children. In the present study, the association between eNOS gene polymorphisms and response to inhaled corticosteroids (ICS) and long-lasting β(2)-agonists (LABAs) was investigated. PATIENTS & METHODS: A total of 81 asthmatic children treated with ICS plus LABAs and 96 healthy controls were genotyped for eNOS G894T and...
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