Article
Exhaled nitric oxide and inducible nitric oxide synthase gene polymorphism in Japanese asthmatics.
Allergology international : official journal of the Japanese Society of Allergology - 1 Jul 2016
Sato Suguru, Wang Xintao, Saito Junpei, Fukuhara Atsuro, Uematsu Manabu, Suzuki Yasuhito, Sato Yuki, Misa Kenichi, Nikaido Takefumi, Fukuhara Naoko, Tanino Yoshinori, Munakata Mitsuru
Abstract excerpt
BACKGROUND: Inducible nitric oxide synthase (iNOS) induced by inflammatory cytokines and iNOS activity in bronchial epithelial cells is a major determinant of fractional exhaled nitric oxide (FeNO) levels. The aim of this study was to investigate the association of iNOS promoter gene polymorphisms and FeNO levels in Japanese asthmatics before the introduction of asthma treatment. METHODS: Asthmatics were...
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