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Article

High glucose induced differential expression of lysyl oxidase and its isoform in ARPE-19 cells.

Current eye research - 1 Jan 2013

Coral Karunakaran, Madhavan Jagadeesan, Pukhraj Rishi, Angayarkanni Narayanasamy

Abstract excerpt

PURPOSE: Lysyl oxidase (LOX) stabilizes the extracellular matrix (ECM) by cross-linking collagen and elastin molecules. In proliferative diabetic retinopathy (PDR), there is ECM remodeling with neovascularization and basement membrane changes. While protease activities are well reported, the role...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein-Lysine 6-Oxidase

Share to Real-Time Polymerase Chain Reaction

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Source

Identifiers

PMID: 22966818
DOI: 10.3109/02713683.2012.720341

Genes

LOX
LOXL1
LOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22966818-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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