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Article

RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response.

Cardiovascular diabetology - 17 Jan 2012

Wang Jiping, Liu Hongxia, Chen Bo, Li Qiang, Huang Xuliang, Wang Liqun, Guo Xiaohua, Huang Qiaobing

Abstract excerpt

BACKGROUND: The role of advanced glycation end products (AGEs) in the development of diabetes, especially diabetic complications, has been emphasized in many reports. Accumulation of AGEs in the vasculature triggers a series of morphological and functional changes in endothelial cells (ECs) and induces an increase of endothelial permeability. This study was to investigate the involvement of RhoA/ROCK-dependent...

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Share to Glycation End Products, Advanced
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22251897
DOI: 10.1186/1475-2840-11-7
PMCID: PMC3280169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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