Article
Impact of lysyl oxidase (G473A) polymorphism on diabetic foot ulcers.
International journal of biological macromolecules - 1 Oct 2017
Pichu Sivakamasundari, Sathiyamoorthy Jayalalitha, Vimalraj Selvaraj, Viswanathan Vijay, Chatterjee Suvro
Abstract excerpt
Lysyl oxidase (LOX) is an extra-cellular matrix-modifying enzyme that has been linked to cell proliferation, metastasis, angiogenesis and wound healing. This study was designed to examine the association of LOX gene polymorphism G473A, G>A, (rs1800449) located in exon 1 of the LOX gene in diabetic subjects with and without diabetic foot ulcers (DFU) and its impact of expression on DFU. Genotypic analysis of 906...
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