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Article

Clinical and Genetic Characterization of Familial Central Precocious Puberty.

The Journal of clinical endocrinology and metabolism - 16 Jun 2023

Tinano Flávia Rezende, Canton Ana Pinheiro Machado, Montenegro Luciana R, de Castro Leal Andrea, Faria Aline G, Seraphim Carlos E, Brauner Raja, Jorge Alexander A, Mendonca Berenice B, Argente Jesús, Brito Vinicius N, Latronico Ana Claudia

Abstract excerpt

CONTEXT: Central precocious puberty (CPP) can have a familial form in approximately one-quarter of the children. The recognition of this inherited condition increased after the identification of autosomal dominant CPP with paternal transmission caused by mutations in the MKRN3 and DLK1 genes. OBJECTIVE: We aimed to characterize the inheritance and estimate the prevalence of familial CPP in a large multiethnic...

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PMID: 36611250
DOI: 10.1210/clinem/dgac763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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