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Article

17β-Estradiol-induced interaction of ERα with NPPA regulates gene expression in cardiomyocytes.

Cardiovascular research - 1 Dec 2012

Mahmoodzadeh Shokoufeh, Pham Thi Hang, Kuehne Arne, Fielitz Britta, Dworatzek Elke, Kararigas Georgios, Petrov George, Davidson Mercy M, Regitz-Zagrosek Vera

Abstract excerpt

AIMS: 17β-Oestradiol (E2) and its receptors (ERα and ERβ) are important regulators of physiological and pathological processes in the cardiovascular system. ER act in concert with other regulatory factors mediating oestrogenic effects. However, the underlying mechanisms modulating ER transcriptional activity are not fully elucidated. To gain better understanding of E2-induced ERα action in the human heart, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22962310
DOI: 10.1093/cvr/cvs281

Genes

NPPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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