Article
HIV-2 EHO isolate has a divergent envelope gene and induces single cell killing by apoptosis.
Virology - 1 Jul 1994
Rey-Cuille M A, Galabru J, Laurent-Crawford A, Krust B, Montagnier L, Hovanessian A G
Abstract excerpt
The human immunodeficiency virus type 2 (HIV-2)-related isolate, referred to as HIV-2 EHO, has been isolated from an Ivory Coast patient with acquired immunodeficiency syndrome (AIDS). Infection of CD4 expressing cells with this highly infectious virus mediates a cytopathic effect characterized by single-cell killing as a consequence of apoptosis. Nucleotide sequence analysis of the HIV-2 EHO genome revealed a...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Apoptosis
- Cells, Cultured
- Genes, env
- Genetic Variation
- Giant Cells
- HIV Envelope Protein gp120
- HIV-2
- Humans
- Molecular Sequence Data
