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Article

Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment.

PloS one - 1 Jan 2012

Sieh Shirly, Taubenberger Anna V, Rizzi Simone C, Sadowski Martin, Lehman Melanie L, Rockstroh Anja, An Jiyuan, Clements Judith A, Nelson Colleen C, Hutmacher Dietmar W

Abstract excerpt

Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in normal and cancer cells. Since two-dimensional (2D) cultures lack the essential characteristics of the native cellular microenvironment, three...

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PMID: 22957009
DOI: 10.1371/journal.pone.0040217
PMCID: PMC3434144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22957009-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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